Khalid Javed Rabbani, Tanveer Mehmood, Furqan Rabbani.
Effect of oral ambroxol HCL treatment on characteristics and recovery of spermatozoa from abnormally high viscous semen in infertile men.
Pak J Med Health Sci Jan ;4(4):387-91.

Objective: The objective of this study was to assess the impact of treating abnormally high viscous semen in infertile men with oral Ambroxol HCl by changing the qualitative and quantitative characteristics of spermatozoa recovered by SWIM UP methods to be use in assisted reproductive techniques (ART). Material and Methods: Fifty sub fertile men producing abnormally high viscous semen participated in this study. The use of oral Ambroxol HCL for improving the liquefaction of semen in these patients leading to impact on the semen specimen produced by the patient was assessed. The spermatozoa recovered with swim up methods were used in ART to treat the sub fertile couple. The method of semen liquefaction used in this study was helpful in the recovery of greater numbers and higher quality spermatozoa (PiO.05) as compared to the conventional method. All the characteristics of spermatozoa were assessed both from quantitative and qualitative point of view in both, the conventional and the Ambroxol liquefied specimens. Conclusions: The liquefaction of abnormally high viscous semen with Oral Ambroxol was shown to be a treatment, which can help significantly in the handling and preparation of abnormally high viscous semen specimen. The oral use of Ambroxol HCL in sub fertile men with abnormally high viscous semen assisted in the recovery of qualitatively and quantitatively improved spermatozoa, which can be used, assisted reproductive techniques.

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