Samina Asghar, Ali Awan, Shumaila Yasin, Saeeda Parveen, Naeema Kauser, Fareed Zafar.
Perinatal and maternal outcome associated with induction of labour.
Pak J Med Health Sci Jan ;4(4):313-4.

Objective: To describe the maternal risk factors and maternal and perinatal outcome associated with labour induction. Design: A cross- sectional study Setting: Gynae unit III SGRH, Lahore, from July 2007- June 2010, a three years study. Patients and methods: All patients admitted for labour induction through outpatient department as well as emergency were included in the study. Main outcome measures: Indication for induction of labour, method of induction, risk factors for induction, success rate of each method and maternal and perinatal outcomes. Results: 5727 patients were admitted for induction of labour during the study period. The indications of labour induction were premature rupture of membranes (OR 3.29, 95% CI, 2.90, 3.73) prolonged pregnancy (OR 4.15,95%CI 3.82,4.50) IUGR, congenital anomaly or intrauterine deaths. The success rate of vaginal delivery was comparable for oxytocin and misoprostol with an overall success rate of 71.5% and C-section rate of 28.5%. Induction of labour was more common in women over 35 years of age OR 1.37, 95% CI 1.14, 1.65. Maternal complications included increase need for uterotonic agents, instrumental delivery, higher rate of c-section, hysterectomy, ICU admission, hospital stay of >7 days and increased need for consultant obstetricians and anesthetists. The adverse perinatal outcomes included low 5 minute Apgar score, low birth weight (RR;0.9;95%CI:0.8-1.1) admission to neonatal ICU, and delayed initiation of breast feeding and perinatal deaths (RR; 0.8; 95% CI: 0.6-1.2). Conclusions: The prevalence of labour induction was 12.5% with a success rate of 71.5%, irrespective of the method used. The most frequent indication was premature rupture of membranes. Induced labour is associated with poor maternal and perinatal outcome.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com