Muhammad Usman Riaz, Masoodur Rauf Khan, Ali Akbar.
Comparison of vacuum assisted closure versus normal saline dressing in healing diabetic wounds.
Pak J Med Health Sci Jan ;4(4):308-12.

Objective: To compare vacuum assisted closure with simple saline soaked dressing in duration of healing wounds in diabetic patients. Study design: Randomized control trial. Place and duration of study: General Surgery Department, Nishter Hospital, Multan.From 28- 03- 2009 to 27 -09- 2009. Methodology: 54 patients of age between 30-60 years of either sex presented with history of superficial diabetic wound involving skin and subcutaneous tissue on any part of body were included in study. They were randomized into 2 groups i.e. A and B. Group A was subjected to vacuum assisted closure and group B to normal saline dressings. Both groups were followed until appearance of 100% granulation tissue over wound surface. Number of days taken were noted. Results: Appearance of granulation tissue was more rapid in vacuum assisted closure group as compared to normal saline dressing group i.e. mean 17.5 days for VAC group and mean 37.5 days for saline soaked gauze dressing (P=0.000). Conclusion: Healing is more rapid in VAC group as compared to normal saline soaked gauze dressings.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com