Mumtaz Ahmed Ahmedani, Iftikhar Ahmed Malik, Sajid Mushtaq, Amir Hussain Khan, Ahsan Ahmed Alvi.
Morphological changes in coronary arteries in ischemic heart disease.
Pak J Pathol Jan ;9(2):32-7.

An autopsy study of ischaemic heart disease was carried out at Armed Forces Institute of Pathology, Rawalpindi from May 1993 to April 1994, to see the morphological changes in coronary arteries. A total of 50 cases were studied. Coronary artery disease was observed relatively more prevalent in younger age group. Severe degree of atherosclerosis was seen in majority (64%) of the patients and predominant involement was in left anterior descending coronary artery. The atheromatous plaques were mainly of concentric type which were mostly lipid rich in composition. Acute coronary lesions including recent thrombosis, plaque fissuring with and without superimposed thrombus formation and intraintimal haemorrhage was seen in 28 cases. A significant percentage of cases (56%) revealed recent thrombus formation which points towards early thrombolytic therapy.

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