Mohammad Kamran Taj, Abdul Majeed Cheema, Imran Taj Hassani, Taj Mohammad Hassani.
Lipid profile in supplementation walnut and almond in hypertension subjects.
Pak J Med Health Sci Jan ;4(3):172-4.

In present study the effects of walnut and almond in specific quantities have been explored on Balochistani (Pakistani) subjects eating natural Balochistani (Pakistani) diet, having hypertension history and taking medicine but without any arthrosclerosis or metabolic disease. The study was conducted on 12 subjects having hypertensive history, who voluntarily participated in the study without any ethnic concern. All the subjects were fed a supplement of walnut and almond 25g each, daily in addition to their diet for a period of 4 weeks and all the subjects completed the nutritional supplementation of 4 weeks of the study. The lipid profile just prior to and after the completion of supplementation was assayed. Total serum cholesterol before and after supplementation was 181.5±8.3 mg/dl and 194.2±6.8 mg/dl respectively; and average variation of the fraction in each individual, a non significant increase of 8.4±3.7% had been observed. The fraction of LDL cholesterol was 115.4±7.1 mg/dl and 121±4.3 mg/dl before and after supplementation respectively, the analysis of this fraction demonstrated a negligible variation due to supplementation. HDL cholesterol value before supplementation was 35.1±3.5 mg/dl and after supplementation was 35.6±3.1 mg/dl. A minor increase of 3% of the fraction had been obtained after the analysis of considering prior value 100 and calculating the subsequent values. The concentration of VLDL prior to the supplementation was 42.6±7.1 mg/dl which was observed to be reduced to 31.2±4.3 mg/dl. In an analysis it was determined that the fraction had been significantly 19.5±8.3% lowered (Mann-Whitney Rank Sum Test P=003) subsequent to the upplementation. The mean value of triglycerides prior to the supplementation was 213.1±35.5 mg/dl which was observed to be reduced to 156.2±21.5 mg/dl. The fraction was significantly 19.5±8.3% lowered subsequent to the supplementation compare to before it. In summation the supplementation of 4 weeks demonstrated increasing trend in total cholesterol, negligible effect on LDL cholesterol fraction, slight increase in HDL cholesterol fraction, significant reduction in VLDL fraction and the concentration of triglycerides. There had been ameliorating and healthier effect on the lipid profile of the hypertensive subjects following combined almond and walnut supplementations.

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