Mohammed Abdul Raziq, Ajwad Farog, Tehseen Iqbal, Aftab Ahmed.
Phenylthiocarbamide (PTC) taste sensitivity and blood groups in a students at Bahawalpur.
J Sheikh Zayed Med Coll Jan ;2(1):152-4.

Background: Phenylthiocarbamide (PTC) taste sensitivity is a genetically controlled trait. ABO and Rh blood groups are also inherited traits. Objectives: We conducted this study to find out any epistatic relationship between the expression of the PTCgene and the blood groups genes. Patients and Method: Among the 739 students, who had given informed consent, 286 were males and 453 were females. Each participant underwent a simple taste test in which a drop of freshly prepared, 0.5% solution of PTC was placed on the dorsum of tongue and the participant was asked to mention the taste perceived. After this he/she was asked to spit out the chemical and to rinse the mouth with water. To find out blood groups, we mixed a drop of blood with antisera i-e anti A, anti B and anti D on a glass slide. By examining for agglutination of RBC\'s, we determined the ABO and Rh blood type of the participants. Results: The percentage of blood group \'A\' among the non-tasters is 22.16 %. Blood group \'B\' is 37.11 % \'AB\' 9.79 %; Blood group \'O\' 30.92 %, Rh positive blood group 87.11 % and Rh-negative blood group 12.89 % among the non-tasters. There is no significant (p>0.05) difference between percentages of non-taster males (27.27 %) and non-taster females (25.66 %). Conclusion: There is no epistatic relationship between PTC gene and blood group genes in our population.

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