Tasneem Z Naqvi.
Role of QRS duration and morphology in predicting response to cardiac resynchronization treatment.
Pak Heart J Jan ;42(1):20-6.

Cardiac resynchronization therapy (CRT) has become a standard treatment for patients with congestive heart failure (CHF) who remain symptomatic despite maximum medical therapy.1 Initially indicated for patients in sinus rhythm, recent guidelines have extended CRT to patients with atrial fibrillation with frequent dependence on ventricular pacing and those with Class I or Class II heart failure symptoms in whom ICD and/or permanent pacemaker is being implanted with anticipated frequent dependence on ventricular pacing.2 What remains unchanged is the requirement of wide QRS (.120 ms) and no inclusion of mechanical asynchrony as a criterion for patient selection. This article reviews evidence behind ECG morphology and duration as determinant for CRT response.

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