Jamalullah M, Atif Rafique, Raheel Ahmed.
Comparison of efficacies of 10% ichthammol glycerine and 3% ciproflaxacin - 1% dexamethasone by means of sustained release of drug by wick method in treatment of otitis externa.
Isra Med J Jan ;3(3):94-6.

OBJECTIVE: To compare the efficacies of 10% Icthammol glycerine and 3% Ciprofloxacin - 1% Dexamethasone by means of sustained release of drug by wick method in treatment of otitis externa. STUDY DESIGN: Quasi experimental study. PLACE AND DURATION OF STUDY: Department of ENT CMH, Rawalpindi from Jan 2007 to Jan 2008. METHODOLOGY: 100 patients who met the inclusion criteria were included in study divided into two equal groups of 50 each by random sampling technique. The patients in group A were given 3% Ciprofloxacin - 1% Dexamethasone and patients in group B were given 10% Icthammol glycerine wick. Both groups of patients were analyzed on third day for reduction in pain by Visual Analogue Scale (VAS) and visible reduction of edema by degree of opening of External Auditory Canal (EAC). RESULTS: Out of 50 patients in group A 76 %( 38) were males and 24 %( 12) females.66 %( 33) patients in group B were males and 34 %( 17) females. On third day in group A, 76 %( 38) patients had marked reduction of pain whereas14 %( 7) had moderate and 10 %( 5) had mild reduction. In group B, on third day 38%(19) patients had marked pain reduction, 30%( 15) had moderate and 32%(16) had mild pain reduction. 86%( 43) patients in group A had visible reduction of external canal edema as compared to 60%(30)patients in group B. CONCLUSION: 3% Ciprofloxacin - 1% Dexamethasone wick is more effective in treating patients of otitis externa as compared to 10% Icthammol glycerine wick.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com