Atiya Mahboob, Munir Akhtar Saleemi.
Topical provocation of fixed drug eruption.
Ann King Edward Med Uni Jan ;4(2):12-3.

To determine the usefulness of topical provocation in the diagnosis of fixed drug eruption, different drugs at various concentrations (2% & 5%) in white soft paraffin were applied on normal or affected skin of 401 patients. Reliable results were obtained with 5% ointment preparations, applied on normal skin. The results were confirmed by peroral provocation, by giving half to full therapeutic dose of the suspected drugs.

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