Farhana Shaikh, Farida Wagan, Kausar Jillani, Khairunnissa Memon.
Pregnancy outcome at maternal age 40 and older.
J Liaquat Uni Med Health Sci May ;11(3):139-42.

OBJECTIVE: The objective of this study was to compare pregnancy outcome of women aged 40 & above with those of 20- 30 year. STUDY DESIGN: Cross-sectional and comparative study. SETTING: Department of obstetrics& Gynecology Peoples University of Medical & Health Sciences Nawabshah. DURATION: From 1st July 2011 to 31st Dec 2011. MATERIAL & METHOD: Consecutive 100 cases of women aged 40 & above and 100 cases of women aged between 20-30 years were included in the study, and labeled as group A & B respectively. All patients were under gone general & physical examination & routine laboratories tests. The biological effects of age on the pregnancy out come were observed, & results were tabulated. RESULT: The mean age for case group was 41.56 ± 2.06 & that for control group 25 ± 2 years. Among the maternal complication of increased maternal age were abortion in early half & preterm labor in second half of pregnancy (10%) & (12%) respectively. Hypertension (14%) & Diabetes (9%) were more common than in younger age group. Risk of fetal malformation (11%) was also three fold more than younger group (2%). Increased rate of c- section (6%) was seen more with advanced maternal age with high parity. CONCLUSION: The advanced maternal age is candidate with high risk of maternal & perinatal morbidity &mortality. Appropriate management can be formulated to ensure better maternal & fetal outcome during pregnancy.

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