Sohail Zia, Yasir Iqbal, Khalid Masood Ashraf, Aneeq Mirza.
Intraocular pressure after IOL implantation with hydroxypropylmethylcellulose 2% vs hydro-implantation.
Pak J Ophthalmol Jan ;29(1):12-5.

Purpose: To compare post-operative intraocular pressure between intraocular lens (IOL) implantation using hydroxypropylmethylcellulose (HPMC) 2% and IOL implantation by hydro-implantation technique after phacoemulsification. Material and Methods: This comparative, prospective study with convenience (Non Probability) sampling was conducted on 100 patients. We divided the patients into two groups. Fifty patients (Group A) had IOL implantation with HPMC 2% and 50 patients (Group B) had IOL with hydro-implantation after phacoemulsification of the lens. Post-operative IOP changes were compared with the preoperative IOP of the same group and between the two groups at 24 hours and 7th post-operative day. A p-value < 0.05 was used as significance cut off point. Results: There was no significant difference in mean pre-operative IOP of both groups (p-value = 0.480). Group A, experienced statistically significant elevation in mean IOP at 24 hours after surgery, over the pre-operative values (p-value: 0.021). Elevation in mean IOP in Group B at 24 hours after surgery was found insignificant (p-value: 0.154). Difference between mean post-operative IOP of the two groups at 24 hours after surgery was also significant (p-value: 0.032). On 7 th day after surgery, mean IOP in both groups had returned to approximately pre-operative values. Moreover, the mean IOP values at 7th post-operative day were also comparable between the two groups (p-value: 0.420). Conclusions: Compared with the use of HPMC for IOL implantation, hydroimplantation of IOL resulted in insignificant rise in post-operative IOP at 24 hours.

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