Saira Bashir, Sarah Riaz, Naila Atif, Bilquis Asuleman, Ghulam Rasul Qureshi.
Morphological spectrum of malignant ovarian tumors in Shaikh Zayed Federal Postgraduate Medical Institute, Lahore.
Pak J Med Health Sci Jan ;5(4):761-3.

Aim: To find out the morphological spectrum of malignant ovarian tumors. Study also tried to relate the age and parity with the tumor Study design: Non-interventional and descriptive study. Material and methods: 21 consecutive malignant ovarian tumor specimens were collected from the Department of Histopathology, Sheikh Zayed Federal Postgraduate Medical Institute, Lahore. Duration of study was 3 months. Study design was non-interventional and descriptive. Cases using cell markers were excluded from the study. The surgical specimens were fixed in 10% formalin solution. Multiple 3-5 mm sections were taken from the tumor with special emphasis on solid foci, area adjacent to ovarian surface and base of papillary formations. In addition sections were taken from the attached fallopian tube, ligaments and capsule of the tumorous ovary. Section from the uninvolved ovary was also taken. Results: Both in age range of 10-20 years and 41-60 years, 38.09% malignant cases were observed. Percentages of malignancy decreased with age i.e., 9.5% in the age of above 60. However in the age range of 21-40 years, the percentage was 14.2. In nulliparous the number of malignant tumors were more as compared to women who were unmarried, primary gravida or multigravida. Most common surface epithelial tumors (57.1%) were papillary cyst adenocarcinoma and endomatrioid carcinoma. Germ cells tumors (38.09%) were immature cystic teratomas and dysgerminoma. Only 01 malignant stromal cell tumor was observed with a percentage of 4.76. Conclusion: Histopathological typing of ovarian tumor is important for early detection and better prognosis of patients.

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