Fazali Wahid, Amir Hamza, Qaisar Khan, Iftikhar Ahmad.
Etiological profile and sensitivity spectrum of isolates from chronic suppurative otitis media studied at a tertiary care hospital.
Pak J Med Health Sci Jan ;6(1):1-4.

Objective: To determine the etiological profile and sensitivity spectrum of microorganisms of chronic suppurative otitis media studied at a tertiary care hospital. Material and methods: This study was conducted at outpatient department of ENT, Head and Neck Surgery, Postgraduate Medical Institute Lady Reading Hospital Peshawar from June 20 10 to June 2011. This study included 285 patients who had discharging ears more than 3 months. The swabs were plated on Mac Conkey agar, Blood agar and Chocolate agar and incubated for 24 to 48 hours at 37oC. Identification of bacterial strains was done by colonial morphology on selective and differential medium. Minimal inhibitory concentrations (MIC) of these antibiotics were monitored according to the guideline of National Committee for Clinical Laboratory Standards (NCCLS). Results: This study included 285 cases constituting 184 male and 101 female, with male:female ratio of 1.8:1. The age of the patients ranged from 08-46 years with mean age of 39.91+S.D 15.27 years. In majority of patients (73.68%) single organism was isolated. Among the isolates Pseudomonas aeruginosa was the commonest (46.31%). The antibiotic susceptibility profile of the bacterial isolates revealed that ciprofloxacin had highest sensitivity against pathogens isolated from CSOM. Conclusion: Pseudomonas aeruginosa is the commonest etiological agent in chronic suppurative otitis media in our set up and ciprofloxacin is the antimicrobial agent with highest sensitivity.

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