Tasleem Akhtar, Muhammad Akram Dogar, Abishek Chaudhary.
Primary Malignant Melanoma of Rectum.
Pak J Med Health Sci Jan ;6(2):507-8.

The vast majority of malignant melanomas arise in the skin, other less common sites include the eyes, leptomeninges. The anorectum is a rare site for noncutaneous melanomas. In fact, primary malignant melanoma of the anorectum accounts for less than 1% of all malignancies in this site and for 0.4%-1.6% of all primary melanomas. Moreover, whether melanomas can arise primarily in the rectum is a subject of great controversy, although Werdin et al and Nicholson et al reported rectal melanomas with adjacent junctional melanocytic proliferation, which suggested that they had arisen from melanocytes located in the rectum. In this paper, we report a case of primary malignant melanoma of the rectum.

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