Naima Mehdi, Mateen Izhar, Nadia Aslam, Rabbia Mehdi.
Carbapenem Resistance among Enterobacteriaceae, a New Challenge.
Pak J Med Health Sci Jan ;6(3):749-51.

Objective: To identify the commonest organism encountering carbapenem resistance among Enterobacteriaceae in indoor as well as outdoor patients irrespective of age and sex at Shaikh Zayed hospital, Lahore. Study design: Cross sectional analytical study. Place of study: Study was carried out at Shaikh Zayed Hospital, Lahore, Sample size: Fifty carbapenem (meropenem) resistant strains of Enterobacteriaceae were included in this study. Material and methods: Initially 50 carbapenem (meropenem) resistant isolates of Enterobacteriaceae were collected from samples received from in-door as well as out-door patients. The organisms were identified by routine laboratory tests including biochemical methods and API 20E system (bioMerieux). Results: Largest numbers of isolates, 44% (22/50), were found to be E. coli, 26% (13/50) isolates were K. pneumoniae, 14% (7/50) Citrobacter species, 12% (6/50) Enterobacter species, 2% (1/50) Providentia rettgeri and 2% (1/50) Morganella morganii (Fig 1). Conclusion: Carbapenem resistance in Enterobacteriaceae is emerging as a new challenge to health care settings as there is no drug in pipeline to treat carbapenem resistant isolates.

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