Atif Masood, Khurram Saleem, Ayub Latif Khawaja, Muhammad Naeem Amin, Munibullah Mirza, Sajjid Sattar Butt, Najeeb Ullah, Sadia Iqbal, Muhammad Atif, Amber Saleemi, Sana Humayun, Muhammad Shiraz Khan Sadiq.
Frequency of Asymptomatic Peripheral Disease in Patients of Metabolic Syndrome.
Pak J Med Health Sci Jan ;6(3):632-6.

Objective: To determine the frequency of asymptomatic peripheral arterial disease (PAD) in subjects with metabolic syndrome. Study design: Descriptive case series study. Setting: This study was conducted in outpatient department of Medicine, Mayo Hospital Lahore. Duration: Six months Subjects: A total of 110 patients with metabolic syndrome were selected for this study. Ankle Brachial Index was calculated by measuring the systolic blood pressure (by Doppler probe) in the brachial, posterior tibial, and dorsalis pedis arteries on both sides. The highest of the four measurements in the ankles and feet is divided by the higher of the two brachial measurements to get ABI. The cut off value for ankle brachial index to diagnose peripheral arterial disease was <0.9. Results: The mean age of the patients was 51.6±8.9 years. There were 63(57.3%) male patients and 47(42.7%) female patients. There were 79(71.8%) patients having history of diabetes mellitus and 66 (60%) patients having history of hypertension. The mean ankle brachial index of the patients was 0.95±0.046. There were 14(12.7%) patients of ankle brachial index of <0.90 and 96(87.7%) patients of ankle brachial index of >0.90. In the distribution of peripheral arterial disease, there were 14(12.7%) patients in whom PAD was present and 96(87.7%) patients in whom PAD was absent. Conclusion: The metabolic syndrome is associated with increased risk of vascular events in peripheral arterial disease patients.

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