Adil Mehmood, Ahsan Khan, Umar Iqbal.
Frequency of Encephalopathy in Cirrhotic Patients Presenting with Upper Gastrointestinal Bleeding.
Pak J Med Health Sci Jan ;6(4):988-91.

Objective: To determine the frequency of hepatic encephalopathy in cirrhotic patients presenting with upper gastrointestinal bleed. Methods: This was a case series (Observational Study) in which hundred cirrhotic patients presenting with upper GI bleed were enrolled. Results: One hundred patients of liver cirrhosis with upper GI Bleed were included in this study. Most of the patients i.e., 61(61%) were positive for HCV RNA alone while another 15 (15%) were positive for both HCV RNA and HBsAg. Out of 100 patients, 62(62%) developed encephalopathy and 38 (38%) were having no evidence of encephalopathy. Conclusion: Most of cirrhotics with Upper GI bleed develop encephalopathy. Preventing Upper GI bleeding can thus contribute significantly in reducing the morbidity and mortality resulting from hepatic encephalopathy.

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