Muhammad Shafiq, Muhammad Akram, Tahir Mahmood.
Diagnostic Sensitivity of Creatine Kinase-MB (CK-MB), Cardiac Troponin T (CTnT) and Cardiac Troponin I (CTnI) in Acute Myocardial Infarction.
Pak J Med Health Sci Jan ;6(4):933-5.
Aim: To compare the diagnostic sensitivity of Creatine Kinase - MB, Cardiac Troponin T and Cardiac Troponin I as preferred serum marker to rule out acute myocardial Infarction. Methods: The study population consisted of 70 patients. Patients from both sexes, with clinical history of typical chest pain for more than 30 minutes in duration with evidence of acute changes of myocardial infarction on ECG were included in the study. This study was conducted to compare the sensitivity of creatine kinase-MB (CK-MB), cardiac troponin T (CTnT) and cardiac troponin I (CTnI) for detection of AMI. Data analysis was performed with Statistical Package for Social Sciences 11.5 (SPSS 11.5). Results: The sensitivity of CK-MB was 100% and 40% as compared to CTnT and CTnI respectively. The sensitivity of CTnT was 51% and 79% as compared to CK-MB and CTnI respectively while the sensitivity of CTnI was100% as compared to both CK-MB and CTnT. Conclusion: It is concluded that CTnl is the preferred, more precise, dependable and cost effective serum marker for detection of AMI as compared to CTnT and CK-MB.
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