Saeed Ahmed, Muhammad Alamgeer Rana, Muhammad Farooq, Atiya Mubarak.
Liver and Body Weight in Albino Rats Associated with Olive Oil Diet Supplemented With Atherogenic Element.
Pak J Med Health Sci Jan ;6(4):875-6.
This was designed to see the possible effects of olive oil on liver and body weight of albino rats. For this purpose, 50 albino rats of eight weeks age were selected and divided into five groups of ten animals each with equal number of males and females. Group I, normal control, was fed on synthetic diet, group II was on low olive oil diet only and group III was on low olive + hypercholesterolemic diet. Group IV was on high olive oil diet only and group V was on hypercholesterolemic diet only for the next 24 weeks. Highly significant difference (p<0.01) was noted in the mean body weight of different animals when compared with zero and 24th week body weights. Comparison of body weights in different groups at 24th week showed increase in body wt and difference was statistically highly significant when compared with control group. Similarly we recorded and compared the weights of liver at the end of study period. Comparison of liver weights in different groups at 24th week showed decrease gain in liver wt. and difference was statistically highly significant when compared with control group. Hence it is concluded that olive oil proved to be beneficial diet. It does not cause decreased gain of hepatic and body weight in low and high concentration when compared with hypercholestremic diet.
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