Saddique Aslam, Muhammad Sajid, Muhammad Ashraf, Akhtar Muneer, Muhammad Farooq.
Comparison of Hydrogen Peroxide and Trichloracetic Acid in Recurrent Oral Aphthous Ulceration Minor.
Pak J Med Health Sci Jan ;6(4):869-71.

Objective: To compare the results of hydrogen peroxide and trichloracetic acid in patients with recurrent oral aphthous ulceration of minor type. Study design: Normative Comparison Study. Setting: DHQ teaching Hospital and private clinics of the authors at Kohat. Study period: January 2010 to December 2010. Patients and methods: Clinically diagnosed 60 patients of recurrent Oral Aphthous ulceration of minor (ROAUM) were included in this study. Patients were distributed into Group A and B having 30 patients in each. Group A having patients treated with 5% hydrogen peroxide and group B of patients treated with 20% trichloroacetic acid (TCA). Both the drugs were used by topical application to all the patients. All the cases were thoroughly evaluated after 6-days of treatment. Reduced or abolished surrounding erythema, tenderness and tingling sensation were used as assessment criteria. Results: Out of total 60 patients of recurrent oral aphthous ulceration minor (ROAUM), there were 15 males (25%) and 45 females (75%) with male to female ratio of 1:3.The age range was 15-50 years where mean age was 35year. In group A, 26 patients (86.6%) got the relief from sumptoms while in group B,only 7 patients (23.4%) went into relief.X2 was aplied to both groups.Chi-square value was 0.66 for which p value is 0.4155 representing non significant results. Presentation of surrounding erythema, tenderness and tingling sensation were found in almost all studied cases. Conclusion: Hydrogen peroxide 5% is a safe, cost effective, easily applicable agent in the treatment of recurrent oral aphthous ulceration minor (ROAUM) type .It is beneficial for such patients in our country.

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