Zafar Ali Khan, Anwar Ali, Riaz Ahmed Warraich.
Comparison of the analgesic effects of peripheral injections of streptomycin/bupivacain and anhydrous glycerol in relieving trigeminal neuralgia.
J Pak Dent Assoc Jan ;19(2):099-104.

OBJECTIVE: Trigeminal neuralgia is an idiopathic, paroxysmal, painful, unilateral affliction of the face, evoked by trivial stimuli to the specific trigger zone, lasting from a few seconds to two minutes. Medical and surgical treatment options are available with varying degree of efficacy. The objective of the study is to compare the analgesic effects of streptomycin/bupivacain versus anhydrous glycerol injection in trigeminal neuralgia. METHODOLOGY: Sixty patients were selected via Non- probability, purposive sampling technique, at the department of oral and maxillofacial surgery, king Edward Medical University/Mayo Hospital Lahore, from 1st June 2008 to 30th Nov 2008. Patients were randomly distributed in to 2 equal groups. In Group A streptomycin/bupvivacain injection was administered, in Group B lml anhydrous glycerol injection was administered. Patients were reviewed after one week, one month, three month and six months post operatively. RESULT: 25(83.34%) patients of Group A had excellent pain relief, 03(l0%) had good results and 02(6.66%) patients had poor results. 28(93.34%) patients of Group B had excellent results, and 2(6.66%) patients had good results while none of the patients had poor results. The p value for these two procedures is not significant (p=0.378). CONCLUSION: The analgesic effect of streptomycin/bupvivacain injection is same as glycerol injection in trigeminal neuralgia. They are simple, quick, and easy to perform, and can be used as outpatient procedures.

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