Muhammad Javad Yousaf, Abdul Khaliq Naveed, Tausif Ahmed, Shakir Khan, Zahid Azeem.
Hypolipidemic effect of extra virgin olive oil in diabetic rats.
J Rawal Med Coll Jan ;16(1):70-2.

Background: To evaluate the effect of monounsaturated fatty acid and phenolic compounds enriched extra virgin olive oil on correction of dyslipidemia in diabetic rats. Methods: In this randomized control trial eighty albino rats of Sprague-Dawley strain weighing 200-250 grams were randomly divided into two groups of 40 rats each. Rats were made diabetic by injecting streptozotocin. Group 1 and Group 2 were given normal rodent diet and extra virgin olive oil supplemented diet respectively for 06 weeks. At the end of experimentation lipid profile was measured. Results: There was significant increase of high density lipoprotein and significant decrease of serum total cholesterol, serum triglycerides and low density lipoprotein of Group II rats when it was compared with Group I (control). Conclusion: Extra virgin olive oil can significantly improve lipid profile in diabetic rats.

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