Sudip Das, Suchibarta Das.
Hydroxyurea – An experience in the management of psoriasis.
J Pak Assoc Derma Jan ;23(4):401-6.

Objective To assess efficacy and safety of hydroxyurea therapy in different types of psoriasis. Patients and methods Eighty patients of chronic plaque psoriasis, generalized pustular psoriasis with more than 20% body surface area and psoriatic erythroderma were included in the prospective nonrandomized study. Results At least good response (up to 50% reduction of PASI) to therapy was noticed in 77.6% (59/76), 11.9% patients did not respond and 10.5% patients worsened. Conclusion Hydroxyurea is effective in the treatment of extensive psoriasis with not so serious side effects.

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