Muhammad Ashfaq, Yasmin Channa, Bader-u-nisa.
Frequency of Iron Deficiency Anemia in Febrile Seizures in Children and Comparison with Febrile Children without Seizures.
Pak Paed J Jan ;38(2):113-7.

Introduction: Iron deficiency anemia is a worldwide problem in pediatric age group. It is associated with febrile seizures. Objectives: 1. To determine the frequency of iron deficiency anemia in patients with febrile seizures. 2. To compare the difference in frequencies of iron deficiency anemia in patients with febrile seizures and febrile patients without seizures. Study Design: Cross sectional analytic study Setting: National Institute of Child Health Karachi. Duration: 6 months from 23rd May 2008 to 23rd November 2008 Subject & Methods: Hundred patients with febrile seizures and hundred patients with only fever were taken. Iron deficiency anemia was defined as Hb <10gm/dl, hematocrit (Hct) <35%, Mean Corpuscular Volume (MCV) <70fl, Mean Corpuscular Hemoglobin (MCH) <24pg and serum ferritin <10ng/ml. Results: Hemoglobin was <10gm% in 74/100 children with febrile seizures as compared to 26/100 febrile children without seizures (P Value <0.01), hematocrit was <35% in 55/100 children with febrile seizures as compared to 26/100 febrile children without seizures (P value <0.01), MCV was <70fl in 73/100 children with febrile seizures as compared to 27/100 febrile =children (P <0.01). MCH was <24 Pg in 77/100 children with febrile seizures as compared to 30/100 febrile children without seizures (P <0.01) and serum ferritin was less than 10 ng/ml in 59/100 children with febrile seizures as compared to only 15/100 in children with fever. (P <0.01). Conclusion: Iron deficiency anemia was more common in children with febrile seizure than in febrile children without seizures.

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