Naveed Faraz, Sehrish, Sajid Abbas.
Role of amaltas and dandasa in controlling biofilm formation of streptococcus sangius.
J Bahria Uni Med Dental Coll Jan ;4(1):16-9.

Objective: To analyze the anti-biofilm activity of naturally occurring substances dandasa (juglans regia) and amaltas (Cassia fistula) against streptococcus sangius. Materials and Methods: This experimental study was carried out at Bahria University Medical and Dental College(BUMDC) Karachi from December 2013 to March 2014.A total of fifty streptococcus sangius samples were taken from oral biofilm and identified using conventional, biochemical, cultural and molecular methods.Biofilm forming activity of these isolates was recorded and then exposed to dandasa and amaltas. Results: Amaltas and Dandasa both in a concentration of 12.5mg/ml and 3.2mg/ml respectively showed good anti-biofilm forming activity against streptococcus sangius. Combination of dandasa with amaltas did not showed more effective inhibitory effect against biofilm formation suggesting an indifferent activity with anti-adhesive index of 0.75 against Streptococcus sangius Conclusion Streptococcus sangius in oral biofilm exhibited biofilm formation which is the cause for antibiotic resistance and provides shelter to other organisms. Amaltas and dandasa provide a good antibiofilm activity individually against Streptococcus sangius

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