Amna Faruqi, Syed Imran Ahmad, Syed Tousif Ahmed.
Early Detection of Cardiac Iron Overload in Thalassemia Major Patients.
J Rawal Med Coll Jan ;18(1):166-9.

Thalassemia Major is an inherited transfusion dependent anaemia.Repeated transfusions lead to iron overloading of body tissues. Iron overload cardiomyopathy is the major cause of death in these patients. Early detection of iron overloading is the solution to managing these patients by iron chelation therapy.Once iron overload cardiomyopathy develops, it becomes extremely difficult to treat or reverse this condition. Different direct and indirect methods have been put forth to assess iron overload. These methods are summarized in this manuscript along with the advantages and disadvantages regarding their use .It is required to establish methods which can be used readily and with sufficient accuracy and at the same time be non invasive and cost effective .

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