Ziauddin A Kashmiri, Umair-ul islam, Shamsunnisa Rashidi, Murtaza Ahsan Ansari.
Post laparoscopic cholecystectomy pain relief. A comparison between Inj. Ketorolac along with infi ltration of Inj. Bupivacaine at operation site & Inj.Ketorolac along with intra-peritoneal infi ltration of Inj. Bupivacaine.
Pak J Surg Jan ;29(2):110-4.

Objective: To study the analgesic effect of injection Ketorolac along with Intra-incisional in-filtration of injection Bupivacaine & compare it with the analgesic effect of injection Ketorolac along with Intra-peritoneal infiltration of injection Bupivacaine. Patients & Methods: This was a prospective randomized double blinded study on 120 patients undergoing laparoscopic cholecystectomy (LC), who were divided in 2 groups, each containing 60 patients. Group B received 30 ml of intra-peritoneal injection of 0.25% Bupivacaine along with injection Ketorolac 30 mg intravenous & group A received 30 mg of injection Ketorolac intravenous along with local infiltration of injection of 0.25% Bupivacaine 5 ml each in all 4 ports at the end of surgery. Post-operatively; an investigator, who was blinded to the procedure, assessed pain using visual analogue scale (VAS) score at 1,6, 12 & 24 hours after surgery. Injection Nalbuphine 5 mg intravenous was administered as rescue analgesic agent when demanded by the patient withn 1st 24 hours. Results: VAS score of the 2 groups, show that the group B has less scores as compared to the group A although it was statistically insignifi cant (p>0.05). Also, rescue analgesic requirement was signifi cantly less in group B as compared to group A (p<0.00). Conclusion: At the end of study we concluded that Intra-peritoneal infi ltration of Bupivacaine along with injection Ketorolac is more eff ective in reducing post LC pain.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com