Guo H, Li J, Liu H, Zhou G, Sun B, Yao Z, Mu D.
The correlation study of 2 micron continuous wave laser between released laser energy and vaporized prostate tissue weights.
Biomedica Jan ;31(3):199-203.

Background and Objectives: To explore the effective method to calculate vaporized tissues during endoscopic prostate surgery using a 2 micron continuous wave laser, by observing the association between vaporized canine prostate tissue weight and released laser energy in an ex-vivo study.The aim was also to assess the extent of thermal damage at different laser power and different modes. Methods: A total of 20 canine prostates were divided into four groups randomly. 2 micron continuous wave laser with output power of 40 W and 70 W was used to ablate tissues in vaporesection or vaporization mode. Vaporized canine prostate tissue weights were measured by recording the pre-and postablation sample weight. Results and Conclusions: With the increase of output power from 40 W to 70 W, ablation efficiency in the vaporesection mode decreased (P = 0. 027, while the ablation efficiency increased in the vaporization mode (P = 0. 001). Our data showed a linear relationship between vaporized prostate tissue weights and released laser energy (Pearson correlation coefficient r = 0. 8689 P = 0. 001) at 70 W output power. Therefore, the amount of prostatic tissues vaporized by 2 micron continuous wave lasers could be calculated from the released laser energy through the linear relationship between vaporized prostate tissue weights and released laser energy. Under the same operating mode there were no significant differences in corresponding depths of coagulation zone. Under the same output power, vaporization produced a significantly deeper coagulation zone than that produced by vaporesection (P < 0. 001), but still within the safety limit.

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