Zareen Aijaz Ghouri, Akhtar Ahmed, Naureen Nizar.
Effect of outflow obstruction on the relative renal function estimation with 99mtc-mag-3 and 99MTC-DMSA.
Pak J Radiol Jan ;21(1):09-12.

BACKGROUND: Several areas of controversy still exist in the selective preference of the method for estimation of relative renal function in patients with outflow obstruction. OBJECTIVES: The aim of this study was to compare the estimation of relative renal function by 99mTc-MAG-3 and 99mTc-DMSA in patients with unilateral outflow obstruction. METH ODS: 99mTc-DMSA scintigraphy was done on 34 patients with outflow obstruction on 99mTc-MAG3 scintigraphy. Relative renal functions were calculated and effect of obstruction on the relative renal function was compared. RESULTS: Good correlation was observed in the estimation of relative renal function estimated by both the methods. One third of the patients had overestimated renal function on 99mTc-DMSA scintigraphy, however the difference was not statistically significant. CONCLUSION: Although 99mTc-DMSA and 99mTc-MAG3 relative renal function estimation show a statistically significant correlation, the over estimations of relative renal function by 99mTc-DMSA in a significant number of case with outflow obstruction needs further clarification.

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