Syed Fahad Ali Zaidi, Faisal G Bhopal, Kamran Faisal Bhopal, Sadaf Faisal Bhopal.
Primary Lymphoma of Duodenum.
J Rawal Med Coll Jan ;18(2):303-5.

Primary lymphoma of the gastrointestinal tract accounts for 5 % of all gastrointestinal tract tumours and only 1 % of all lymphomas.Diffuse, large cell lymphoma of B-cell origin (DLBC) is the predominant histologic type of primary extra-nodal lymphoma originating from a gastrointestinal site. Primary nonHodgkin's lymphoma of the duodenum is an even more rarely occurring primary tumor of the gastrointestinal (GI) tract which constitutes less than 12% of all non-Hodgkin’s lymphoma (NHL).,1,2 Periampullary lymphoma or lymphomatous involvement of ampulla of Vater is even much more rare a phenomenon to be seen. It is difficult to differentiate periampullary lymphoma from epithelial carcinoma of these sites on basis of clinical judgement or on basis of radiological findings Accurate histopathological diagnosis is required to chalk out the plan of what could be the optimal treatment strategy. The principal determinants of choice of therapy and prognosis of the patient depends upon cell type, grade, and presence of disseminated disease.

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