Lubna K Jadoon, Hasan Raza, Minhaj Maqbool, Bashir Ahmed, Sumaira Mushtaq, Aniqa Jabeen, Muhammad A Memon.
Impact of attenuation correction on segmental score analysis of myocardial perfusion imaging.
Pak J Nuclear Med Jan ;4(1):64-74.

Aims To assess the impact of attenuation correction in reducing artifacts and the influence of gender and body mass on the effect of attenuation correction. Methods 102 patients referred for myocardial perfusion imaging (mean age: 53.24 ± 12.7) were enrolled. They all underwent stress (dynamic or pharmaceutical) and rest Tc-99m MIBI studies. Polar maps of the left ventricular cavity with 17 segments of both the noncorrected (NC) and attenuation corrected (AC) images were generated and semiquantitatively analyzed by software automatically. Results Segmental scores in inferior wall were significantly low (p < 0.05) particularly in male population irrespective of BMI. AC didn’t do significant impact in score values in anterior wall of female population (p > 0.05). AC also generated artifactual perfusion defects in apex and apical segments (p <0.05). Conclusion This study demonstrates that Attenuation correction using hybrid SPECT-CT improved average myocardial perfusion uptake in inferior regions and this technique is more beneficial to male populace.

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