Samina Shiekh, Zubair Anwar, Tania Mirza, Aqeela Khurshid, Adeela Khurshid, Iqbal Ahmad.
Total parenteral nutrition (TPN): role of riboflavin (vitamin B2) and cyanocobalamin (vitamin B12).
Baqai J Health Sci Jan ;18(1):31-47.

Total parenteral nutrition (TPN) replaces and maintains essential nutrients in patients in whom oral or tube feedings are contraindicated or inadequate. A nutritional assessment must be carried out before initiating TPN in order to determine nutritional needs and any metabolic changes due to the patient’s underlying condition, medications or concurrent therapies. In addition to carbohydrates, proteins and fats, certain amounts of micronutirents are also added to TPN solutions. These micronutrients include electrolytes, vitamins, and trace minerals. This review highlights some basic concepts regarding the use and formulation of TPNs along with their advantages and disadvantages and the importance of water soluble vitamins B2 and B12 in human nutrition.

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