Muhammad Imran, Manqoosh-ur Rehman, Tanveer Ahmad Kang.
Efficacy of Intra Articular Injections in Different Grades of Osteoarthritis of Knee.
Med Forum Jan ;3(1):49-52.

Objectives: To assess the efficacy of intra articular injections in different grades of osteoarthritis of knee. Study Design: Descriptive study Place and Duration of Study: This study was conducted at the Department of Orthopedics Railway Hospital Rawalpindi and Ibn-e-Seina Hospital & Research Institute Multan started from June 2008 to June 2012. Materials and Methods: This study included 90 patients of either sex having mild, moderate and severe grades of osteoarthritis of knee based on radiographic findings. A study proforma was designed in which bio-statics and results of the study were recorded. Five intra-articular injections of hyaluronic acid were given on weekly basis and patients were assessed for pain and functional activity at intervals of 0, 6 and 12 weeks by KSKS, WOMAC and VAS scoring system. These patients were selected consecutively. Results: In this study patients with mild and moderate grades of osteoarthritis of knee showed improvement but patients with severe grades of osteoarthritis either showed no response or less improvement. Conclusion: Intra-articular injection of hyaluronic acid is an effective modality in early stages of osteoarthritis of knee.

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