Husnain Bashir, Qazi Abdul Saboor, Abubakar Hilal, Saulat Siddique, Amber Malik, Qazi Muhammad Tufail, Adnan Salim Malik, Wasim Ahmed, Mohammad Abdul Rehmaan.
Frequency of left ventricular systolic dysfunction in patients with end stage renal disease on maintenance haemodialysis.
J Cardiovascular Dis Jan ;12(3):71-5.

INTRODUCTION: Cardiovascular diseases are the most common cause of mortality in patient with end-stage renal disease. Diagnosis of congestive heart failure (CHF) with concomitant renal failure presents a particular challenge. Patients with end-stage renal disease have three key mechanical contributors to CHF including pressure overload, volume overload, and cardiomyopathy. Approximately 20% of patients undergoing hemodialysis have a diagnosis of CHF. MATERIALS & METHODS: All 130 patients fulfilling the inclusion/exclusion criteria presenting to Haemodialysis Unit, Sheikh Zayed Hospital, Lahore were included in the study after informed consent. Two dimensional, M mode, Doppler and color Doppler echocardiography in the left lateral decubitus position, using 3.5 MHz transducer by the researcher was used. The left ventricular ejection fraction (EF) and fractional shortening (FS) was measured as indices of LV systolic function and the measurements were taken according to American society of echocardiography guideline. RESULTS: Patients were 18 to 70 years of age, majority of the patients were between 41-50 years i.e. 30%(n=39), mean and SD was calculated as 39.43+4.21 years, 63 (48.46%) were male and 67 (51.54%) were females, frequency of left ventricular systolic dysfunction was seen in 7 (5.38%) patients with end stage renal disease maintenance haemodialysis. CONCLUSION:The frequency of Left Ventricular systolic dysfunction is considerable among patients with end stage renal disease in first year of regular maintenance haemodialysis. Therefore, it is recommended that every patient who is diagnosed as ESRD or known patient of ESRD on maintenance haemodialysis, should be investigated for LV systolic dysfunction to prioritize them for early initiation of renal replacement therapy. It is also required that every setup should have their surveillance in order to know the frequency of the problem. KEY WORDS: End stage renal disease, maintenance haemodialysis, frequency, Left Ventricular systolic dysfunction.

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