Hassan Suleman Malik, Huma Arshad Cheema, Muhammad Almas Hashmi, Nadia Waheed, Aftab Anwar, Muhammad Nadeem Anjum.
Frequency of Hepato-biliary Disorders in Children Presenting at The Children’s Hospital & The Institute of Child Health, Lahore, A Tertiary care Referral Center.
Pak Paed J Jan ;41(1):42-7.

Hepato biliary disorders encompass a diverse spectrum of disorders with varying manifestations and degree of morbidity and lethality. Objectives: To determine the frequency of hepato-biliary disorders among the patients admitted over the past three years. Study Design: Retrospective descriptive study Place and Duration: Department of Pediatric Gastroenterology Hepatology & Nutrition; The Children’s Hospital & The Institute of Child Health, Lahore. January 2013 to December 2015 Subjects and Methods: Patients with hepato-biliary disorders admitted over 03 years; January 2013 to December 2015 were included. Data were retrospectively analyzed from hospital record. Incomplete records or duplications were excluded. Qualitative variables such as frequency of various disorders and their gender distribution were described in terms of frequencies and percentages. Age at presentation was described as mean and standard deviation. Results: Total 644 patients, 01 month to 18 years of age, were entered (mean 5.73 + 4.31); males 406 and females 238. Most common hepato biliary disorder found was Idiopathic Chronic Liver Disease (87) followed by Biliary Atresia (80), Neonatal Hepatitis (69), Wilson Disease (66), Chronic Hepatitis C (40), Acute Hepatitis A Virus Infection (39), Autoimmune Hepatitis (36), Budd chairi Syndrome (36), GSD (36), Galactosemia (35), Congenital Hepatic Fibrosis (27), Chronic Hepatitis B (24), Portal Vein Thrombosis (22), Choledochal Cyst (22), PFIC (12), Tyrosenemia (8) and Hemophagocytic lymphohistiocytosis (3). Conclusion: Hepato-biliary disorders are common in children with Idiopathic Chronic Liver Disease, Biliary Atresia, Neonatal Hepatitis, Wilson Disease and Viral hepatitis the most common entities.

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