Syeda Batool Mazhar, Samia Janjua.
Recurrent familial hydatidiform mole.
J Pak Inst Med Sci Jan ;6(1,2):383-6.

Gestational trophoblastic disease is rare. Recurrent gestational trophoblastic disease occurs in 0.6-2.6% of subsequent pregnancies. The rate.for a third hydatidiform mole (H.M.) goes up to 15-28%. There are no reliable data on the incidence of consanguinity or family history on the incidence of hydatidiform mole. There have been reports of familial occurence of gestational trophoblastic disease (GTD) in literature. In the case reports presented here two out of a total of four sisters suffered from recurrent hydatidiform molar pregnancies. A third sister was found to have characteristic appearance of a molar pregnancy on ultrasound scan but she ref used treatment. None of these sisters have given birth to a live child.

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