Wasif Farman, Shazia Yusuf, Raja Amjad Mahmood.
Predictive Value Of Calcium Scoring On Non Contrast CT Coronary Angiography In Assessing Coronary Artery Disease Taking Post Contrast CT Coronary Angiograpy As Gold Standard.
Isra Med J Jan ;8(1):46-51.

OBJECTIVE: To determine the predictive value of calcium scoring on non-contrast CT coronary angiography taking contrast enhanced CT coronary angiography (CE CTA) as gold standard. To observe association of major risk factors for coronary artery disease (CAD) with Calcium Scoring (CS). STUDY DESIGN: A Cross Sectional Study. th th PLACE AND DURATION: At Radiology Imaging Department of Capital Hospital, CDA, Islamabad from 15 October, 2012 to 28 September, 2015. METHODOLOGY: The study included 111 symptomatic patients, referred by cardiologist, with suspected coronary artery disease performed in Radiology Imaging Department of Capital Hospital, CDA Islamabad. The patients had undergone non-contrast CT for calcium scoring followed by contrast enhanced CT coronary angiography. Patients' data was analyzed using SPSS version 16. RESULTS: The study showed that sixty four patients had calcium score of more than zero. Out of these, fifty seven (89%) had CAD on CE CTA. Forty seven patients had calcium score of zero and CE CTA demonstrated no CAD in thirty five (74.4%). Male patients had more percentage of calcium score than female. There were significant numbers of patients with associated major CAD risk factors. The number of patients with associated hypertension, lack of exercise, family history, smoking and dyslipidemia were 75%, 70%, 54%, 52.6% and 42% respectively. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 82.6 %, 83 %, 89 %, 74.4% and 82.8 % respectively. CONCLUSION: CS is a reliable non-invasive screening test for the detection or exclusion of CAD. Most patients with high calcium score had CAD and a high percentage of patients with zero calcium score did not have any significant CAD.

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