Muhammd Jamil, Munir Ahmad Abbasi, Haidar Zaman.
Outcome of eclampsia in patients admitted to ICU at a tertiary care teaching hospital.
Khyber Med Uni Med J Jan ;5(4):203-6.

Objective: To determine the outcome of eclampsia patients admitted to intensive care unit (ICU) of Ayub Teaching Hospital Abbottabad. Methodology: This retrospective descriptive study was carried out at the ICU of Ayub Teaching Hospital Abbottabad, Pakistan. Case records of all patients presenting with eclampsia to the ICU from April 1, 2010 to 30 September 2011 were included in the study. Case records were reviewed and information about patients was collected and tabulated. The results were reported as frequency and percentages. Results: A total of 116 eclamptic patients were admitted to ICU in this period. Of these 30 (25.9%) patients developed complications and 18 (15.5%) patients died. Two (1.7%) patients left the ICU against medical advice and 2 (1.7%) were referred for nephrologist opinion. Sixty five (56.03%) of these patients were primigravida and 51 (43.97%) were multigravida. Almost all deaths occurred in summer months. Six (5.2%) patients developed acute tubular necrosis (ATN), 5 (4.3%) developed disseminated intravascular coagulation (DIC) while 4 (3.45 %) patients each developed abruptio placentae, HELLP syndrome and septicaemia. Other complications included acute renal failure (2.6%), and post-partum haemorrhage (2.6%). Conclusion: Eclampsia is responsible for significant maternal morbidity and mortality in our set up. Mortality rate is 15.5% while ATN and DIC are the commonest complications of eclampsia in our patients.

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