Saera Afghan, Ara Yasmeen.
Abnormal Uterine Bleeding (AUB) A Clinicopathological Study of 150 Cases.
Ann Pak Inst Med Sci Jan ;9(4):201-4.

Objective: To study the histopathology of endometrial biopsies in abnormal uterine bleeding and clinicopathological correlation. Study Design: Retrospective randomized study. Place and Duration: From September 2012 to August 2013 at MCH Department of Gynaecology and Obstetrics, unit II, Pakistan Institute of Medical Sciences Islamabad. Materials and Methods: Retrospective study of 150 patients with abnormal uterine bleeding (AUB) for a period of one year from September 2012 till August 2013. Patients presenting to MCH Center PIMS OPD with complaint of abnormal uterine bleeding were assessed. A detailed history was followed by general physical examination, hysteroscopy and endometrial biopsy, which was then sent for histopathological examination. Result: The major symptoms with which the patients presented was menorrahgia 34.6% , polymenorrahgia 27.3%, metrorrahgia 20.6%, polymenorrhea in 4.7% cases, postmenopausal bleeding 4.6%, hypomenorrhea 3.3%, oligomenorrhea 2.0%, continuous PV bleeding 2.0%, secondary amenorrhea 0.6%. Histopathology of endometrium was analyzed which includes Proliferative phase 34.6%, Secretory phase 24%, Estrogen dominant 22%, Pill pattern 7.3%, Hyperplasia 5.8%, Anovulatory endometrium 4%, Aries Stella pattern 2%, Chronic endometritis 2%, Senile atrophy 0.6%, Endometrial carcinoma 0.6%. Conclusion: in our study dysfunctional uterine bleeding was the most common cause of Abnormal Uterine Bleeding followed by fibroid uterus less then 3cm. Histopathology revealed majority of endometrium in proliferative phase.

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