Sahibzada Saeed Jan, Jan-i Alam, Farhat Rahman.
The relationship of LDL-C in diabetic and non-diabetic stroke patients District Swat.
J Saidu Med Col Jan ;7(2):122-6.

BACKGROUND: Diabetes mellitus is a well recognized risk factor for acute stroke, resulting in a greater ischemic to hemorrhagic stroke ratio in the people with diabetes compared with the general population. As there are controversies in different international studies regarding the level of LDL-C in diabetic and non-diabetic stroke patients, so there is an intense need to evaluate the level of LDL-C in diabetic and non-diabetic stroke patients (Control group) in our setup. OBJECTIVE: The aim of this study was to evaluate the association of Low Density Lipoprotein-Cholesterol (LDL-C) level in the diabetic and non-diabetic stroke patients. MATERIAL AND METHOD: This was a cross-sectional study, comprised of 100 subjects, 50 were diabetic and 50 were nondiabetic stroke patients of ages between 30 to 90 years. The study duration was 6 months. The subjects underwent a detailed history and examination. Individuals with a history of medications known to affects body composition, patients on anti-coagulants and having a history of blood dyscrasias like leukemia, thalasemia, polycythemia and having clotting disorders, extradural and intradural hemorrhage as a cause of stroke were excluded from the study. Fasting (overnight) as well as random (two hours after meal) blood samples were drawn from the participants for biochemical assays. The serum LDL-C level, blood sugar (random and fasting), blood pressure (systolic and diastolic) of diabetic stroke subjects were compared with Non-diabetic stroke subjects. RESULTS: The LDL-C level was not significantly high in diabetic as compared to non-diabetic stroke subjects. CONCLUSION: Low-density lipoprotein cholesterol (LDL-C) is not an independent predictor of macrovascular disease such as stroke.

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