Mohammad Sajjad, Sania Tnveer Khattak, Muhammad Asif, Imran-ud Din.
Histological pattern of chorionic villi is patients suffering from spontaneous miscarriage.
J Saidu Med Col Jan ;7(2):86-8.

BACKGROUND: Chorionic villi develops from chorion and enter the endometrium in form of microscopic finger like projections and contain capillaries for blood flow and transfer of nutrients from mother to the fetus. The objective of this study was to see the histological pattern of chorionic villi in spontaneous miscarriage patients. OBJECTIVE: To determine Histological pattern of chorionic villi is patients suffering from spontaneous miscarriage MATERIALS AND METHODS: This cross sectional descriptive study was conducted in Pathology department, Bannu Medical College Bannu Khyber Pakhtunkhwa. Pakistan. The duration was five years from January 2012 to December 2016. A total of 64 specimen of spontaneous miscarriage of endometrial curettage specimen were analysed. All spontaneous miscarriage endometrial specimen of any age were included in the study, exclusion criteria was autolysed, insufficient specimen and endometrium of induced miscarriage. Blocks were prepared, sections taken, slides were prepared, dried ,stained and mounted and reported by histopathologist. The data were analysed in Statistical Package for Social Sciences (SPSS) version 16 for frequencies with percentages and mean with standered deviation. RESULTS: In this study the mean age was 23.65 (16 to 50 years). The common age group of spontaneous was 16-25 years followed by 26-35 years. Amongst the 64 specimen 11(17.18%) cases were normal chorionic villi, 19(29.68%) showed hydropic changes, 15(23.42%) cases showed fibrinoid degeneration, 11 (17.18%) cases showed hyalinization, 6 (9.37%) cases showed molar changes and 01 (1.56%) case showed choriocarcinoma. CONCLUSION: Histologic examination of endometrium is a reliable method of diagnosing routine spontaneous miscarriage cases, also may of help in some cases in identification of the cause of miscarriage.

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