Saadia Akram, Muhammad Waqas Nisar Ahmed, Farhana Sami, Mohammad Aamir Mirza, Samina Rizvi, Rizwana Barakzai, Syed Mehmood Hasan.
Association Between Incidental Diagnosis of Adenomyosis on Histopathology to the Clinical Symptomatology.
Ann Jinnah Sindh Med Uni Jan ;3(1):25-8.

Objectives: To determine association between incidental diagnosis of adenomyosis on histopathology and clinical symptomatology Methodology: This hospital-based cross-sectional study was conducted at Lady Dufferin Hospital, Karachi, Pakistan. A structured standardized proforma was used to collect data between January 2014 to Dec 2016 from the pathological laboratory data on surgical hysterectomies. The data comprised of clinical, physical, and histological examination. The analysis was made on association between incidental diagnosis of adenomyosis on histopathology and the clinical symptomatology and diagnosis. Results: Two hundred and seventy-four abdominal hysterectomies were studied. Out of 274 study subjects, 97 cases (35.4%) were diagnosed as adenomyosis after histopathological examination. Among the study subjects, the mean age was 42.77 + 6.96. Seventy-nine cases (81.44%) were fertile and had children. There was a history of abortion in 16 cases (16.49%). The commonest clinical symptom associated with adenomyosis was menorrhagia in 38 cases (39.17%). Clinically, adenomyosis was diagnosed in only 5 (5.15%) women. History of hormonal therapy (primolut) was available in only three cases (3.09%). Not a single case (0%) showed association of primary infertility with adenomyosis. Our study found no clear association between adenomyosis and any specific histological type and stage of endometrium. Conclusion: This hospital-based study showed that adenomyosis is a neglected diagnosis and is mostly incidentally diagnosed in various cases of clinically diagnosed dysfunctional uterine bleeding. Since it is found to be much more common than clinically expected, a proper investigation to exclude adenomyosis prior to surgery is recommended by various diagnostic modalities. Key words: Adenomyosis, incidental adenomyosis, clinical symptomatology of adenomyosis, diagnosis of adenomyosis

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