Fauzia Hashmi, Naila Tariq.
Importance of Serum Iron and Total Iron Binding Capacity as Important Tools in the Diagnosis of Iron Deficiency Anaemia.
Ann Jinnah Sindh Med Uni Jan ;3(1):22-4.

Objective: To evaluate the importance of serum ferritin in the diagnosis of iron deficiency anaemia as compared to other diagnostic parameters Methodology: Serum iron and Total Iron Binding Capacity (TIBC) was evaluated among three groups with group-A comprising male patients (n=150), group-B comprising females (n=150) and group-C designated for pregnant women (n=150). All groups were falling in the age group of 20 to 40 years. These patients were from medical and Obstetrics/ Gynae OPD of JPMC, Karachi. The subjected parameters were analyzed on instruments Beckman Coulter and Selectra using Colorimetric method. Results: The results indicated that in group A, 48/150 (32%) participants showed less value of serum iron from the normal range (50-168 ug/dl) while their TIBC was reported to be inversely proportional to serum iron deficiency, elevated from the normal recommended range for males and females (250-450ug/dl) in 29/48 (19.3%) cases. Similarly, in group B, 56/150 (37%) cases were positive for serum iron deficiency while TIBC was raised in 41/56 (73.2%). Group C reported lower value of serum iron in 83/150 (55.3%) participants and raised TIBC in 62/83 (74.6%). Conclusion: On the basis of the above findings, it is concluded that the estimation of serum iron and TIBC gives accurate analysis and these are important tools in the diagnosis of Iron Deficiency Anaemia. Key words: Serum iron, TIBC, iron deficiency anaemia

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