Abubakar Sheikh, Muhammad Atif Saleem Agwan, Muhammad Amin, Muhammad Athar Khan, Ismail Sheikh, Syed Imran Shah.
Comparison Of Ibuprofen And Celecoxib For Controlling Post Endodontic Pain.
J Pak Dent Assoc Jan ;23(3):106-11.

OBJECTIVE: The objective of this study was to compare the efficacy of ibuprofen and celecoxib in controlling post endodontic pain. METHODOLOGY: A Quasi Experimental study was conducted in the Operative Dentistry Department of Altamash Institute of Dental Medicine during fourteen months study period. One hundred patients who required root canal treatment and fulfilled the criteria of the study were equally divided into two groups, A and B. Patients in group A were given Ibuprofen and those in group B were administered Celecoxib for 2 days following treatment. Patients rated their pain on a visual analog scale at initial and then 4, 8, 12, 24 and 48 hours after first visit of endodontic therapy. Data analysis was performed through SPSS version-13.0. Independent samples t-test was used with p-value <0.05 considered as significant. RESULTS: There was no statistically significant difference in post endodontic pain between the groups of patients taking Ibuprofen and Celecoxib. (p value: Pre-op 0.54, 4 hrs 0.62, 8 hrs 0.86, 12 hrs 0.57, 24 hrs 0.61, 48 hrs 0.09) CONCLUSIONS: Ibuprofen and Celecoxib have similar efficacy in controlling post endodontic pain.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com