Afifa Waheed, Humera Yasmeen, Nabeela Shami.
BACTERIAL VAGINOSIS; Comparison of vaginal metronidazole with vaginal clindamycin in the treatment of bacterial vaginosis.
Professional Med J Jan ;22(8):989-95.

Bacterial vaginosis is the most common vulvovaginal infection and represents the 35% of all the infections occurring in women in the reproductive age. Serious forms of can induce several complications such as spontaneous preterm labour and preterm birth, late miscarriage and postpartum endometritis, PID, infertility, vaginal cuff infection and postabortal sepsis. Objective: To compare the efficacy of vaginal metronidazole and vaginal clindamycin in the treatment of bacterial vaginosis. Study Design: Interventional: Quasi experimental study. Setting: Obstetrics outpatient department, Ghurki Trust Teaching Hospital, Lahore. Duration of study: Six months i.e. from 01-01-2009 to 30-06-2009. Results: Mean age of patients was found to be 24.33 years. In the 100 patients enrolled, no statistically significant difference was found between Clindamycin 2% vaginal cream compared with metronidazole 0.75% vaginal gel using Amsell’s criteria. Metronidazole has a failure rate of 13% while failure rate was 6% in the clindamycin group. Conclusion: A 3 day regimen of clindamycin 2% vaginal cream was as effective as 5 day regimen of metronidazole 0.75% vaginal gel in the treatment of bacterial vaginosis.

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