Bukhari S, Nawaz H, Tariq S, Muneer A.
In Vitro Antimicrobial Activity Of Aloe Vera Gel On Selected Urinary Pathogens.
Biomedica Jan ;33(1):39-42.

Background and Objectives: Urinary tract infection is a common bacterial infection in the general population with an estimated incidence of 18 per thousand persons. It is more common in women and the reported annual incidence is 12%. The problematic factors in urinary tract infection are its high incidence, recurrence and increasing resistance of uropathogens towards antibiotics. The objective of the study was to find a herbal anti bacterial alternative to avoid side effects and other problems of antibiotics. The anti microbial activity of Aloevera Gel is known. The purpose was to observe the effect of Aloevera Gel (in vitro) against some selected uropathogens mainly involved in causing urinary tract infection. Methods: In vitro activity of Aloe Vera Gel was studied on 3 selected urinary micro organisms i.e., Ecoli, Staphylococcus aureus and Pseudomonas aeruginosa, collected from the positive urine cultures of UTI patients. 30 cases were included consisting of 10 for every urinary pathogen. Aloe Vera Gel was obtained by incising longitudinally the fresh and mature leaf of the Aloevera plant and collecting the pare-chymatous colorless Gel from them. 0.1 ml of the gel was introduced into the 7 mm holes bored into the nutrient agar media inoculated with the selected urinary pathogens and incubated at 37oC for 24 hours. Zones of inhibition were measured in mm. Results: Aloevera Gel was found to have anti bacterial effect against the selected uropathogens. It produced zones of inhibition against E-coli, Staphylococcus aureus and Pseudomonas aeruginosa. Its anti bacterial activity against these organisms was of 76.9%, 75% and 40% respectively. Conclusion: Aloevera Gel exhibited varied anti microbial activity against all the said uropathogens by producing zone of inhibition against them. Aloevera Gel expressed almost equal anti bacterial activity against E-coli and Staphylococcus aureus with comparatively less effect against Pseudomonas aeruginosa.

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