Zainab Subhan, Sarah Shami, Muzammil Jamil Ahmed Rana.
Comparison of prophylactic intraligamentary injection of piroxicam and lignocaine for management of postoperative endodontic pain.
Pak Oral Dental J Jan ;36(3):480-3.

The primary goal of endodontic treatment is to hermetically seal the entire root canal system by an adequate biomechanical preparation and provide conducive conditions for periradicular healing. Even with the utmost care, some patients may experience pain or flare up after the treatment. The objective of this study was to compare the mean postoperative endodontic pain using prophylactic intraligamentary injection of piroxicam and lignocaine in teeth with irreversible pulpitis. Various anti-inflammatory agents have been used intraorally or intramuscularly in order to control post treatment pain. In the present study role of intraligamentary injection was investigated in controlling post-endodontic discomfort. Present study was carried out from June 2014 to December 2014 in the Department of Operative Dentistry, AFID, Rawalpindi. A total of 120 patients were scored for this purpose which were equally divided into two groups (Group A and Group B). Group-A patients received supplemental intraligamentary injection of 0.4ml of 20mg/ml piroxicam as an active agent. Group-B patients received supplemental intraligamentary injection of 0.4ml of 2% lignocaine containing 1: 100,000 epinephrine as an active agent. Mean age of the patients was 41.92 (±14.1) and 40.10 (±13.3) in group-A and B respectively. Piroxicam group demonstrated significant decrease in pain intensity after 48 hours (Mean± SD=0.40 ± 0.49) compared to lignocaine having mean pain values of 1.37 (±0.93) at 48 hours. There was statistically significant difference in reduction of pain score between two groups (p<0.001). Intraligamentary injection of piroxicam can be considered an effective method for reducing post-endodontic pain.

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