Irfan Waheed Kh A, Bushra Karim Javaid, Humayun Iqbal Khan, Khadija Irfan.
Chronic Renal Failure due to Obstructive Uropathy in Children.
Ann King Edward Med Uni Jan ;8(3):194-5.

Obstructive uropathy is an important cause of chronic renal failure (CRF) in children, and is both preventable and reversible to some extent. We conducted a prospective study of all new paediatric cases of CRF between 1991-2000 to find out the contribution of obstructive uropathy to childhood CRF. There were 25 (22 male & 3 females) cases of obstructive uropathy out of a total of 135 patients, with a mean age of 4.5 years. The commonest cause was posterior urethral valves (68%), followed by urolithiasis (20%), bladder neck obstruction (8%) and post-traumatic strictures (4%). Posterior urethral valves accounted for 77.3% of the obstructive uropathy in male children. Early detection is possible using antenatal screening, renography and ultrasonography, allowing therapeutic interventions before renal failure sets in.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals -