Ehmer Al Ibran, Sidra Meraj, Mahwish Nasim, Maria Khan, Masood Hussain Rao.
Pattern of Microorganisms Isolated from Flame Burn Wounds, and Their Trends of Susceptibility to Antibiotic During Past Three Years.
J Dow Uni Health Sci Jan ;7(2):49-53.

Objective: To determine the prevalent bacteria causing wound infection and their trend of susceptibility toantibiotics over a period of last three years in flame burn cases. This is an observational descriptive studyconducted at the Burns Center, Civil Hospital Karachi.Methods: All available wound swabs culture and sensitivity reports of flame burn victims admitted during theperiod of January 2009 - December 2011 were included. Wound swab was usually taken from the burnt areathat appears clinically deep, with pus or with thick eschar. In laboratory, microbial growth on any of the inoculatedplates gram staining, biochemical identification and antibiotic sensitivity by disc diffusion method was done.Statistical analysis was done through SPSS version 17.0 to determine the frequencies, mean ± SD and associationof these culture and sensitivity of isolated organisms with antibiotics.Result: Wound swab culture and sensitivity reports of 382 flame burnt patients were assessed. No significantrelation was found between age, gender and duration of stay of a patient and bacterial colonization. Cultureand sensitivity reports showing isolates of Staphylococcus aureus, Pseudomonas aeruginosa, Enterobacteraerogenes, Escherichia coli, Klebsiella pneumonia, Proteus as major microorganisms. Pseudomonas Aeroginosawas found to be the most commonly isolated microorganism 36.6%(f=140). It was found to be highly sensitivewith Imipenam throughout our period of study whereas Staphlococcus Aureus was found highly sensitivewith vancomycin, doxicillin and Amoxicillin+ clauvilaunic acid (in sequence with their percentage sensitivityin 2011).Conclusion: During the last three years, a change in susceptibility of antibiotic was found. Some of the antibioticswhich were 100 sensitive with common bacteria’s were posted to resistant during this period. Therefore, repeatedanalysis of microbes prevalent in Burn Care facility should be carried out in order to determine change in theirsensitivity spectrum to commonly prescribed antimicrobials to rule out wrong selection of empirical antibiotics.

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