Muhammad Alam, Jehan Ara, Taqdees Iftakhar, Syed Aslam Shah.
A Comparasion of Povidon Iodine & 2% Chlore hexadine Gluconate Scrubs in preventing Post Operative Wound Infections.
Ann Pak Inst Med Sci Jan ;13(1):23-6.

Objective: Comparison of Povidone Iodine & Chlor hexadine Gluconate scrubs in preventing postoperative wound infections in clean and clean contaminated surgeries. Methodology: A randomized control trial was conducted at Rawal Institute of Health Sciences (RIHS) Islamabad, a tertiary care hospital having a large catchment area in Islamabad. Two departments’ i.e. General surgery and department of Gynae & Obs who shared the surgical work participated in this study. The duration of trial was from May 2016 to December 2016. A proforma was designed to be filled in by the treating doctor to record demographic data, surgical procedure and prophylactic antibiotics used. A total of 114 patients included in study were divided in two groups, and the disinfectant 10% povidone iodine for group 1 and 2% chlore hexadine gluconate for group II. The patients were selected randomly for both groups. The patients were observed and postoperatively followed on weekly basis for a month to observe any sign of surgical site infection(SSI). Results: Out of total 114 patients from two departments,57 patients were in each group I&II. In group, I six (6) patients (10.5%) developed infection, while in group II only 1 patient (1.7%) got infected (p<0.005). The pathogens seen were Strep pyogenes, E coli, Pseudomonas and Steph aureus. Conclusion: Chlorehexadin Gluconate was found to have a lower infection rate as compared to Povidone Iodine in prevention of surgical site infections(SSI).

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com